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Herpes Simplex Virus 1 Open Reading Frames O and P Are Not Necessary for Establishment of Latent Infection in Mice

Open reading frame (ORF) O and ORF P partially overlap and are located antisense to the γ(1)34.5 gene within the domain transcribed during latency. In wild-type virus-infected cells, ORF O and ORF P are completely repressed during productive infection by ICP4, the major viral transcriptional activat...

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Autors principals: Randall, Glenn, Lagunoff, Michael, Roizman, Bernard
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC102098/
https://ncbi.nlm.nih.gov/pubmed/10982346
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