Zinc Finger Structures in the Human Immunodeficiency Virus Type 1 Nucleocapsid Protein Facilitate Efficient Minus- and Plus-Strand Transfer

The nucleocapsid protein (NC) of human immunodeficiency virus type 1 (HIV-1) has two zinc fingers, each containing the invariant metal ion binding residues CCHC. Recent reports indicate that mutations in the CCHC motifs are deleterious for reverse transcription in vivo. To identify reverse transcrip...

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Publié dans:	J Virol
Auteurs principaux:	Guo, Jianhui, Wu, Tiyun, Anderson, Jada, Kane, Bradley F., Johnson, Donald G., Gorelick, Robert J., Henderson, Louis E., Levin, Judith G.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2000
Sujets:	Replication
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102094/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10982342/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.19.8980-8988.2000
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