Genetics of Mouse Mammary Tumor Virus-Induced Mammary Tumors: Linkage of Tumor Induction to the gag Gene

Retroviruses are believed to induce tumors by acting as insertional mutagens that activate expression of cellular protooncogenes. Indeed, almost 90% of mouse mammary tumor virus (MMTV)-induced mammary tumors in C3H/He mice show upregulation of Int protooncogenes. We have analyzed three different MMT...

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Main Authors: Hook, Lauren M., Agafonova, Yelena, Ross, Susan R., Turner, Stephanie J., Golovkina, Tatyana V.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Transformation and Oncogenesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC102082/
https://ncbi.nlm.nih.gov/pubmed/10982330
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