Alternative Proteolytic Processing of Mouse Mammary Tumor Virus Superantigens

Mouse mammary tumor viruses express a superantigen essential for their life cycle. It has been proposed that viral superantigens (vSags) require processing by prohormone convertases (PCs) for activity. We now observe, using a panel of mutant forms of potential PC cleavage sites and in vitro cleavage...

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Hauptverfasser: Denis, François, Shoukry, Naglaa H., Delcourt, Marc, Thibodeau, Jacques, Labrecque, Nathalie, McGrath, Helen, Munzer, J. Scott, Seidah, Nabil G., Sékaly, Rafick-Pierre
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC111805/
https://ncbi.nlm.nih.gov/pubmed/10708421
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