Mutational Analysis of the Adeno-Associated Virus Type 2 (AAV2) Capsid Gene and Construction of AAV2 Vectors with Altered Tropism

Adeno-associated virus type 2 (AAV2) has proven to be a valuable vector for gene therapy. Characterization of the functional domains of the AAV capsid proteins can facilitate our understanding of viral tissue tropism, immunoreactivity, viral entry, and DNA packaging, all of which are important issue...

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izdano v:	J Virol
Principais autores:	Wu, Pei, Xiao, Wu, Conlon, Thomas, Hughes, Jeffrey, Agbandje-McKenna, Mavis, Ferkol, Thomas, Flotte, Terence, Muzyczka, Nicholas
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2000
Teme:	Gene Therapy
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102071/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10954565/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.18.8635-8647.2000
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