Severe Murine Lung Immunopathology Elicited by the Pathogenic Equine Herpesvirus 1 Strain RacL11 Correlates with Early Production of Macrophage Inflammatory Proteins 1α, 1β, and 2 and Tumor Necrosis Factor Alpha

The CBA mouse model was used to investigate the immunopathology induced in the lung by the pathogenic equine herpesvirus 1 (EHV-1) strain RacL11 in comparison to infection with the attenuated vaccine candidate strain KyA. Intranasal infection with KyA resulted in almost no inflammatory infiltration...

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Bibliographic Details
Main Authors: Smith, Patrick M., Zhang, Yunfei, Grafton, Warren D., Jennings, Stephen R., O'Callaghan, Dennis J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC102042/
https://ncbi.nlm.nih.gov/pubmed/11024132
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