The Brucella abortus CcrM DNA Methyltransferase Is Essential for Viability, and Its Overexpression Attenuates Intracellular Replication in Murine Macrophages

The CcrM DNA methyltransferase of the α-proteobacteria catalyzes the methylation of the adenine in the sequence GAnTC. Like Dam in the enterobacteria, CcrM plays a regulatory role in Caulobacter crescentus and Rhizobium meliloti. CcrM is essential for viability in both of these organisms, and we sho...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Robertson, Gregory T., Reisenauer, Ann, Wright, Rachel, Jensen, Rasmus B., Jensen, Allen, Shapiro, Lucille, Roop, R. Martin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Genetics and Molecular Biology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101938/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10852881/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.12.3482-3489.2000
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