The Brucella abortus CcrM DNA Methyltransferase Is Essential for Viability, and Its Overexpression Attenuates Intracellular Replication in Murine Macrophages

The CcrM DNA methyltransferase of the α-proteobacteria catalyzes the methylation of the adenine in the sequence GAnTC. Like Dam in the enterobacteria, CcrM plays a regulatory role in Caulobacter crescentus and Rhizobium meliloti. CcrM is essential for viability in both of these organisms, and we sho...

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Hauptverfasser: Robertson, Gregory T., Reisenauer, Ann, Wright, Rachel, Jensen, Rasmus B., Jensen, Allen, Shapiro, Lucille, Roop, R. Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
Schlagworte:
Genetics and Molecular Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC101938/
https://ncbi.nlm.nih.gov/pubmed/10852881
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