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Regulation of rRNA Transcription Is Remarkably Robust: FIS Compensates for Altered Nucleoside Triphosphate Sensing by Mutant RNA Polymerases at Escherichia coli rrn P1 Promoters

We recently identified Escherichia coli RNA polymerase (RNAP) mutants (RNAP β′ Δ215–220 and β RH454) that form extremely unstable complexes with rRNA P1 (rrn P1) core promoters. The mutant RNAPs reduce transcription and alter growth rate-dependent regulation of rrn P1 core promoters, because the mut...

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主要な著者: Bartlett, Michael S., Gaal, Tamas, Ross, Wilma, Gourse, Richard L.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2000
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC101898/
https://ncbi.nlm.nih.gov/pubmed/10715005
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