Regulation of rRNA Transcription Is Remarkably Robust: FIS Compensates for Altered Nucleoside Triphosphate Sensing by Mutant RNA Polymerases at Escherichia coli rrn P1 Promoters

We recently identified Escherichia coli RNA polymerase (RNAP) mutants (RNAP β′ Δ215–220 and β RH454) that form extremely unstable complexes with rRNA P1 (rrn P1) core promoters. The mutant RNAPs reduce transcription and alter growth rate-dependent regulation of rrn P1 core promoters, because the mut...

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Dettagli Bibliografici

Pubblicato in:	J Bacteriol
Autori principali:	Bartlett, Michael S., Gaal, Tamas, Ross, Wilma, Gourse, Richard L.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Genetics and Molecular Biology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101898/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10715005/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.7.1969-1977.2000
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