Immunostimulatory properties of phosphorothioate CpG DNA containing both 3′–5′- and 2′–5′-internucleotide linkages

Synthetic oligodeoxyribonucleotides containing CpG-dinucleotides (CpG DNA) in specific sequence contexts activate the vertebrate immune system. We have examined the effect of 3′-deoxy-2′–5′-ribonucleoside (3′-deoxynucleoside) incorporation into CpG DNA on the immunostimulatory activity. Incorporatio...

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Опубликовано в::	Nucleic Acids Res
Главные авторы:	Yu, Dong, Kandimalla, Ekambar R., Zhao, Qiuyan, Cong, Yanping, Agrawal, Sudhir
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Oxford University Press 2002
Предметы:	Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101845/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11917022/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.7.1613
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