Mutational Analysis of the Helicobacter pylori Vacuolating Toxin Amino Terminus: Identification of Amino Acids Essential for Cellular Vacuolation

The functional importance of the amino terminus of the Helicobacter pylori vacuolating cytotoxin (VacA) was investigated by analyzing the relative levels of vacuolation of HeLa cells transfected with plasmids encoding wild-type and mutant forms of the toxin. Notably, VacA's intracellular activity wa...

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Bibliografiske detaljer

Udgivet i:	Infect Immun
Principais autores:	Ye, Dan, Blanke, Steven R.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2000
Fag:	Molecular and Cellular Pathogenesis
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101768/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10858259/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.7.4354-4357.2000
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