DNA-Based Immunization with Trypanosoma cruzi Complement Regulatory Protein Elicits Complement Lytic Antibodies and Confers Protection against Trypanosoma cruzi Infection

A complement regulatory protein (CRP) of Trypanosoma cruzi was evaluated as a vaccine candidate in a murine model of experimental T. cruzi infection. Recombinant CRP derived from an Escherichia coli expression system and a plasmid encoding the full-length crp structural gene under the control of a e...

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Hlavní autoři: Sepulveda, Pilar, Hontebeyrie, Mireille, Liegeard, Pascal, Mascilli, Alexia, Norris, Karen A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
Témata:
Fungal and Parasitic Infections
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC101717/
https://ncbi.nlm.nih.gov/pubmed/10948115
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