DNA-Based Immunization with Trypanosoma cruzi Complement Regulatory Protein Elicits Complement Lytic Antibodies and Confers Protection against Trypanosoma cruzi Infection

A complement regulatory protein (CRP) of Trypanosoma cruzi was evaluated as a vaccine candidate in a murine model of experimental T. cruzi infection. Recombinant CRP derived from an Escherichia coli expression system and a plasmid encoding the full-length crp structural gene under the control of a e...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Sepulveda, Pilar, Hontebeyrie, Mireille, Liegeard, Pascal, Mascilli, Alexia, Norris, Karen A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Fungal and Parasitic Infections
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101717/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10948115/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.9.4986-4991.2000
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