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Arginine 109 to glutamine mutation in a girl with ornithine carbamoyl transferase deficiency.

We studied DNA from 29 families with at least one member with ornithine carbamoyl transferase (OCT) deficiency and have found a mutation in the TaqI site within exon 5 of the OCT gene in a female presenting at the age of 21 months. Hybridisation with site specific oligonucleotides shows that the mut...

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Pubblicato in:J Med Genet
Autori principali: Strautnieks, S, Rutland, P, Malcolm, S
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 1991
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1017166/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1757964/
https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jmg.28.12.871
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