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Analysis of mitochondrial DNA in Leber's hereditary optic neuropathy.

Twenty-eight patients from 25 maternal lineages with Leber's hereditary optic neuropathy (LHON) were investigated by restriction enzyme analysis for the presence or absence of the point mutation described by Wallace et al. The mutation was identified in 18 of 25 (72%) families with LHON. This p...

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Detalles Bibliográficos
Main Authors: Poulton, J, Deadman, M E, Bronte-Stewart, J, Foulds, W S, Gardiner, R M
Formato: Artigo
Idioma:Inglês
Publicado: 1991
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1017112/
https://ncbi.nlm.nih.gov/pubmed/1770533
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