Recombinant Mycobacterium bovis BCG Expressing Pertussis Toxin Subunit S1 Induces Protection against an Intracerebral Challenge with Live Bordetella pertussis in Mice

The recent development of acellular pertussis vaccines has been a significant improvement in the conventional whole-cell diphtheria-pertussis-tetanus toxoid vaccines, but high production costs will limit its widespread use in developing countries. Since Mycobacterium bovis BCG vaccination against tu...

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Autori principali: Nascimento, Ivan P., Dias, Waldely O., Mazzantini, Rogerio P., Miyaji, Eliane N., Gamberini, Marcia, Quintilio, Wagner, Gebara, Vera C., Cardoso, Diva F., Ho, Paulo L., Raw, Isaias, Winter, Nathalie, Gicquel, Brigitte, Rappuoli, Rino, Leite, Luciana C. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
Soggetti:
Microbial Immunity and Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC101688/
https://ncbi.nlm.nih.gov/pubmed/10948100
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