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Mutation size and age at onset in Huntington's disease.

The mutation responsible for Huntington's disease is a polymorphic (CAG)n repeat sequence which is expanded on affected chromosomes. The number of repeat units observed on 229 affected chromosomes varied from 27 to 102, while the control chromosomes showed a range of 7 to 34 repeats. There was...

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Hlavní autoři: Craufurd, D, Dodge, A
Médium: Artigo
Jazyk:Inglês
Vydáno: 1993
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1016633/
https://ncbi.nlm.nih.gov/pubmed/8133496
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