Age at onset in Huntington's disease and methylation at D4S95.

Age at onset in Huntington's disease (HD) is variable and is influenced by parental sex, paternal age, and genetic background. Several recent models have tried to explain this variable expressivity by invoking parental imprinting and related aspects of epigenetic inheritance. Some of these mech...

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Detalhes bibliográficos
Main Authors: Reik, W, Maher, E R, Morrison, P J, Harding, A E, Simpson, S A
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1016295/
https://ncbi.nlm.nih.gov/pubmed/8474105
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