Induction of a Polarized Th1 Response by Insertion of Multiple Copies of a Viral T-Cell Epitope into Adenylate Cyclase of Bordetella pertussis

The adenylate cyclase (CyaA) of Bordetella pertussis delivers the N-terminal catalytic domain into the cytosol of a large number of eukaryotic cells, in particular, professional antigen-presenting cells. This allows the delivery of CD8(+) T-cell epitopes to the major histocompatibility complex class...

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Bibliografiske detaljer

Udgivet i:	Infect Immun
Principais autores:	Dadaglio, Gilles, Moukrim, Zhora, Lo-Man, Richard, Sheshko, Valeria, Sebo, Peter, Leclerc, Claude
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2000
Fag:	Microbial Immunity and Vaccines
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101660/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10858196/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.7.3867-3872.2000
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