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Molecular mechanisms in Angelman syndrome: a survey of 93 patients.

Angelman syndrome (AS) results from a lack of maternal contribution from chromosome 15q11-13, arising from de novo deletion in most cases or rarely from uniparental disomy. These families are associated with a low recurrence risk. However, in a minority of families, more than one child is affected....

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Autores principales: Chan, C T, Clayton-Smith, J, Cheng, X J, Buxton, J, Webb, T, Pembrey, M E, Malcolm, S
Formato: Artigo
Lenguaje:Inglês
Publicado: 1993
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1016595/
https://ncbi.nlm.nih.gov/pubmed/7905534
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