Tuberculosis DNA Vaccine Encoding Ag85A Is Immunogenic and Protective When Administered by Intramuscular Needle Injection but Not by Epidermal Gene Gun Bombardment

Immunogenicity and protective efficacy of a DNA vaccine encoding Ag85A from Mycobacterium tuberculosis were compared in BALB/c and C57BL (B6 and B10) mice immunized by intramuscular (i.m.) needle injection or epidermal gene gun (gg) bombardment. In BALB/c mice, gg immunization could induce elevated...

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Hlavní autoři: Tanghe, Audrey, Denis, Olivier, Lambrecht, Bénédicte, Motte, Vinciane, van den Berg, Thierry, Huygen, Kris
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2000
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC101658/
https://ncbi.nlm.nih.gov/pubmed/10858194
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