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RFLP analysis for APP 717 mutations associated with Alzheimer's disease.

Familial Alzheimer's disease (FAD) has been shown to be associated with three distinct point mutations within the same codon of the amyloid precursor protein (APP) gene. The mutation identified in the Indiana kindred is a G-->T transversion at the first position of the codon for amino acid 7...

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Autori principali: Zeldenrust, S R, Murrell, J, Farlow, M, Ghetti, B, Roses, A D, Benson, M D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1993
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1016419/
https://ncbi.nlm.nih.gov/pubmed/7686976
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