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X inactivation patterns in females with Alport's syndrome: a means of selecting against a deleterious gene?

The patterns of X chromosome inactivation in 43 females from families segregating classic Alport's syndrome (AS) (X linked hereditary nephritis with deafness) have been analysed. AS carrier females have a most variable clinical course. The aim of the study was to establish whether there was any...

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Main Authors: Vetrie, D, Flinter, F, Bobrow, M, Harris, A
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1016101/
https://ncbi.nlm.nih.gov/pubmed/1404298
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