A Novel Action of the Proton Pump Inhibitor Rabeprazole and Its Thioether Derivative against the Motility of Helicobacter pylori

The motility of Helicobacter pylori was maximum at 37°C and at pH 6. A newly developed proton pump inhibitor, rabeprazole (RPZ), and its thioether derivative (RPZ-TH) markedly inhibited the motility of H. pylori. The concentrations of the drug necessary to inhibit 50% of the motility were 0.25, 16,...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Tsutsui, Nanako, Taneike, Ikue, Ohara, Tatsuki, Goshi, Satoshi, Kojio, Seiichi, Iwakura, Nobuhiro, Matsumaru, Hiroyuki, Wakisaka-Saito, Noriko, Zhang, Hui-Min, Yamamoto, Tatsuo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Mechanisms of Action: Physiological Effects
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101604/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11036024/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.11.3069-3073.2000
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