Purification and Characterization of a Cytotonic Protein Expressed In Vitro by the Live Cholera Vaccine Candidate CVD 103-HgR

Cholera vaccines developed by the deletion of CTX genes from Vibrio cholerae induce a residual reactogenicity in up to 10% of vaccinees. A novel cytotonic agent named secreted CHO cell elongating protein (S-CEP) was purified from culture supernatants of CVD 103-HgR (Levine et al., Lancet ii:467–470,...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Sathyamoorthy, Venugopal, Hall, Robert H., McCardell, Barbara A., Kothary, Mahendra H., Ahn, Susie J., Ratnayake, Shashikala
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Molecular and Cellular Pathogenesis
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101575/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10992523/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.10.6062-6065.2000
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