Expression of Interleukin-9 Leads to Th2 Cytokine-Dominated Responses and Fatal Enteropathy in Mice with Chronic Schistosoma mansoni Infections

Mice infected with Schistosoma mansoni develop Th2 cytokine-mediated granulomatous pathology that is focused on the liver and intestines. In this study, transgenic mice constitutively expressing IL-9 were infected with S. mansoni and the outcome of infection was determined. Eight weeks after infecti...

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Main Authors: Fallon, Padraic G., Smith, Philip, Richardson, Emma J., Jones, Frances J., Faulkner, Helen C., Van Snick, Jacques, Renauld, Jean-Christophe, Grencis, Richard K., Dunne, David W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC101565/
https://ncbi.nlm.nih.gov/pubmed/10992513
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