Expression of Interleukin-9 Leads to Th2 Cytokine-Dominated Responses and Fatal Enteropathy in Mice with Chronic Schistosoma mansoni Infections

Mice infected with Schistosoma mansoni develop Th2 cytokine-mediated granulomatous pathology that is focused on the liver and intestines. In this study, transgenic mice constitutively expressing IL-9 were infected with S. mansoni and the outcome of infection was determined. Eight weeks after infecti...

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Publicado en:	Infect Immun
Autores principales:	Fallon, Padraic G., Smith, Philip, Richardson, Emma J., Jones, Frances J., Faulkner, Helen C., Van Snick, Jacques, Renauld, Jean-Christophe, Grencis, Richard K., Dunne, David W.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2000
Materias:	Fungal and Parasitic Infections
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101565/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10992513/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.10.6005-6011.2000
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