T-Cell-Dependent Antibody Response to the Dominant Epitope of Streptococcal Polysaccharide, N-Acetyl-Glucosamine, Is Cross-Reactive with Cardiac Myosin

Autoantibodies against myosin are associated with myocarditis and rheumatic heart disease. In this study, the antigenic cross-reactivity of myosin and N-acetyl-glucosamine (GlcNAc), the dominant epitope of Group A streptococcal polysaccharide, was examined. Six antimyosin monoclonal antibodies (MAbs...

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Publié dans:	Infect Immun
Auteurs principaux:	Malkiel, Susan, Liao, Li, Cunningham, Madeleine W., Diamond, Betty
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2000
Sujets:	Host Response and Inflammation
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101540/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10992488/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.10.5803-5808.2000
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