Mycobacterium bovis BCG Induces Similar Immune Responses and Protection by Rectal and Parenteral Immunization Routes

We compared cellular immune responses to rectal, subcutaneous, and intradermal administration of Mycobacterium bovis BCG for 5 to 20 weeks in mice, guinea pigs, and macaques. Strong lymphoproliferative responses were induced in spleen cells after in vitro stimulation with purified protein derivative...

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Bibliographic Details
Main Authors: M, Abolhassani, Lagranderie, M., Chavarot, P., Balazuc, A.-M., Marchal, G.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC101519/
https://ncbi.nlm.nih.gov/pubmed/10992467
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