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Mycobacterium bovis BCG Induces Similar Immune Responses and Protection by Rectal and Parenteral Immunization Routes

We compared cellular immune responses to rectal, subcutaneous, and intradermal administration of Mycobacterium bovis BCG for 5 to 20 weeks in mice, guinea pigs, and macaques. Strong lymphoproliferative responses were induced in spleen cells after in vitro stimulation with purified protein derivative...

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Detalhes bibliográficos
Main Authors: M, Abolhassani, Lagranderie, M., Chavarot, P., Balazuc, A.-M., Marchal, G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC101519/
https://ncbi.nlm.nih.gov/pubmed/10992467
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