Bacterial Immunoglobulin Superantigen Proteins A and L Activate Human Heart Mast Cells by Interacting with Immunoglobulin E

Human heart mast cells (HHMC) have been identified in heart tissue, perivascularly, and in the intima of coronary arteries. In vitro activation of isolated HHMC induces the release of vasoactive and proinflammatory mediators (histamine, tryptase, and cysteinyl leukotriene C(4) [LTC(4)]). We investig...

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Publié dans:	Infect Immun
Auteurs principaux:	Genovese, Arturo, Bouvet, Jean-Pierre, Florio, Giovanni, Lamparter-Schummert, Bärbel, Björck, Lars, Marone, Gianni
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2000
Sujets:	Host Response and Inflammation
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101500/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10992448/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.10.5517-5524.2000
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