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Bacterial Immunoglobulin Superantigen Proteins A and L Activate Human Heart Mast Cells by Interacting with Immunoglobulin E

Human heart mast cells (HHMC) have been identified in heart tissue, perivascularly, and in the intima of coronary arteries. In vitro activation of isolated HHMC induces the release of vasoactive and proinflammatory mediators (histamine, tryptase, and cysteinyl leukotriene C(4) [LTC(4)]). We investig...

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Detalhes bibliográficos
Main Authors: Genovese, Arturo, Bouvet, Jean-Pierre, Florio, Giovanni, Lamparter-Schummert, Bärbel, Björck, Lars, Marone, Gianni
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC101500/
https://ncbi.nlm.nih.gov/pubmed/10992448
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