δ-Aminolevulinic acid cytotoxic effects on human hepatocarcinoma cell lines

BACKGROUND: Acute Intermittent Porphyria is a genetic disorder of heme metabolism, characterized by increased levels of porphyrin precursors, δ-aminolevulinic acid (ALA) and porphobilinogen (PBG). ALA has been reported to generate reactive oxygen species and to cause oxidative damage to proteins, su...

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Bibliographic Details
Main Authors: De Siervi, Adriana, Vazquez, Elba S, Rezaval, Carolina, Rossetti, María V, del Batlle, Alcira M
Format: Artigo
Language:Inglês
Published: BioMed Central 2002
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC101407/
https://ncbi.nlm.nih.gov/pubmed/11914144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-2-6
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