Wird geladen...

Involvement of conserved histidine, lysine and tyrosine residues in the mechanism of DNA cleavage by the caspase-3 activated DNase CAD

The caspase-activated DNase (CAD) is involved in DNA degradation during apoptosis. Chemical modification of murine CAD with the lysine-specific reagent 2,4,6-trinitrobenzenesulphonic acid and the tyrosine-specific reagent N-acetylimidazole leads to inactivation of the nuclease, indicating that lysin...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Korn, Christian, Scholz, Sebastian Richard, Gimadutdinow, Oleg, Pingoud, Alfred, Meiss, Gregor
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC101349/
https://ncbi.nlm.nih.gov/pubmed/11884629
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!