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CD4 T cells in the rheumatoid joint are oligoclonally activated and change during the course of disease.
OBJECTIVE--To assess the nature of T cell receptor (TCR) utilisation by CD4 T cells in the rheumatoid joint. METHODS--Sequencing of the joining (NDJ) region of TCR beta chain mRNA isolated from synovial fluid CD4 T cells was performed in three patients in order to determine if oligoclonal expansion...
Kaydedildi:
Asıl Yazarlar: | , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
1995
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1005581/ https://ncbi.nlm.nih.gov/pubmed/7763112 |
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