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CD4 T cells in the rheumatoid joint are oligoclonally activated and change during the course of disease.

OBJECTIVE--To assess the nature of T cell receptor (TCR) utilisation by CD4 T cells in the rheumatoid joint. METHODS--Sequencing of the joining (NDJ) region of TCR beta chain mRNA isolated from synovial fluid CD4 T cells was performed in three patients in order to determine if oligoclonal expansion...

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Detalhes bibliográficos
Main Authors: Khazaei, H A, Lunardi, C, So, A K
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1005581/
https://ncbi.nlm.nih.gov/pubmed/7763112
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