Effects of methotrexate on glycosaminoglycan production by scleroderma fibroblasts in culture.

OBJECTIVE--To determine the effects of increasing concentrations of methotrexate on the proliferation and glycosaminoglycan (GAG) synthesis of cultured dermal fibroblasts from patients with scleroderma. METHODS--Cultured dermal fibroblasts from nine patients with scleroderma and nine normal voluntee...

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Autores principales: van den Hoogen, F H, van der Kraan, P M, Boerbooms, A M, van den Berg, W B, van Lier, H J, van de Putte, L B
Formato: Artigo
Lenguaje:Inglês
Publicado: 1993
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1005174/
https://ncbi.nlm.nih.gov/pubmed/8257212
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