Cargando...

6-Thioguanine nucleotide accumulation in erythrocytes during azathioprine treatment for systemic connective tissue diseases: a possible index for monitoring treatment.

BACKGROUND: Owing to adverse pharmacokinetics, azathioprine treatment may fail to induce a satisfactory clinical response in systemic connective tissue diseases. The major intracellular cytotoxic metabolites of azathioprine are 6-thioguanine nucleotides (6TGNs). METHODS: To assess whether the erythr...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Schmiegelow, K, Kriegbaum, N J
Formato: Artigo
Idioma:Inglês
Publicado: 1993
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1004996/
https://ncbi.nlm.nih.gov/pubmed/8447695
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!