Inhibition of interleukin 1 beta induced rat and human cartilage degradation in vitro by the metalloproteinase inhibitor U27391.

Interleukin 1 induced proteoglycan loss from cartilage in vitro was prevented by a biochemical inhibitor of metalloproteinase activity. The inhibitor also partially relieved the inhibition of proteoglycan synthesis caused by interleukin 1. The loss of glycosaminoglycan by rat and human femoral head...

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Bibliographische Detailangaben
Hauptverfasser: Seed, M P, Ismaiel, S, Cheung, C Y, Thomson, T A, Gardner, C R, Atkins, R M, Elson, C J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1993
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1004953/
https://ncbi.nlm.nih.gov/pubmed/8427512
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