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Role of nucleotidyltransferase motifs I, III and IV in the catalysis of phosphodiester bond formation by Chlorella virus DNA ligase

ATP-dependent DNA ligases catalyze the sealing of 5′-phosphate and 3′-hydroxyl termini at DNA nicks by means of a series of three nucleotidyl transfer steps. Here we have analyzed by site-directed mutagenesis the roles of conserved amino acids of Chlorella virus DNA ligase during the third step of t...

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Sonraí Bibleagrafaíochta
Main Authors: Sriskanda, Verl, Shuman, Stewart
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2002
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC100343/
https://ncbi.nlm.nih.gov/pubmed/11842101
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