Transcription Factor HIF-1 Is a Necessary Mediator of the Pasteur Effect in Mammalian Cells

The ability to respond to differential levels of oxygen is important to all respiring cells. The response to oxygen deficiency, or hypoxia, takes many forms and ranges from systemic adaptations to those that are cell autonomous. Perhaps the most ancient of the cell-autonomous adaptations to hypoxia...

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Autores principales: Seagroves, Tiffany N., Ryan, Heather E., Lu, Han, Wouters, Bradly G., Knapp, Merrill, Thibault, Pierre, Laderoute, Keith, Johnson, Randall S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Cell Growth and Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC100265/
https://ncbi.nlm.nih.gov/pubmed/11313469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.10.3436-3444.2001
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