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Threonine-11, Phosphorylated by Rad3 and ATM In Vitro, Is Required for Activation of Fission Yeast Checkpoint Kinase Cds1

Fission yeast Cds1 is phosphorylated and activated when DNA replication is interrupted by nucleotide starvation or DNA damage. Cds1 enforces the S-M checkpoint that couples mitosis (M) to the completion of DNA synthesis (S). Cds1 also controls replicational stress tolerance mechanisms. Cds1 is regul...

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Autors principals: Tanaka, Katsunori, Boddy, Michael N., Chen, Xiao-Bo, McGowan, Clare H., Russell, Paul
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC100261/
https://ncbi.nlm.nih.gov/pubmed/11313465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.10.3398-3404.2001
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