Kinetics of p53 Binding to Promoter Sites In Vivo

Downstream target genes of p53 are thought to mediate its tumor-suppressive activity, but it is unknown whether differential transactivation of these genes is regulated at the level of p53 binding to their promoters. To address this issue, p53 binding in vivo to consensus sites in the p21(Waf1), MDM...

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Bibliografiska uppgifter
Huvudupphovsmän: Szak, Suzanne T., Mays, Deborah, Pietenpol, Jennifer A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2001
Ämnen:
Transcriptional Regulation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC100259/
https://ncbi.nlm.nih.gov/pubmed/11313463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.10.3375-3386.2001
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