Mechanism for Mutational Inactivation of the Tumor Suppressor Smad2

Transforming growth factor β (TGF-β) is a potent natural antiproliferative agent that plays an important role in suppressing tumorigenicity. In numerous tumors, loss of TGF-β responsiveness is associated with inactivating mutations that can occur in components of this signaling pathway, such as the...

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Detalhes bibliográficos
Principais autores: Prunier, Celine, Ferrand, Nathalie, Frottier, Bertrand, Pessah, Marcia, Atfi, Azeddine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC100252/
https://ncbi.nlm.nih.gov/pubmed/11313456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.10.3302-3313.2001
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