Naturally Occurring Clostridium perfringens Nontoxic Alpha-Toxin Variant as a Potential Vaccine Candidate against Alpha-Toxin-Associated Diseases

Clostridium perfringens mutant strain 121A/91 shows neither enzymatic (phospholipase C) nor hemolytic activity. Nevertheless, the cpa gene and the corresponding alpha-toxin variant are detectable. Vaccination with this genetically constructed alpha-toxin variant, rAT121/91, induces antibodies capabl...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Infect Immun
Principais autores:	Schoepe, Heike, Pache, Christian, Neubauer, Axel, Potschka, Heidrun, Schlapp, Tobias, Wieler, Lothar H., Baljer, Georg
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2001
Fag:	Molecular Pathogenesis
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC100128/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11598102/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.11.7194-7196.2001
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!