B-Cell Deficiency Suppresses Vaccine-Induced Protection against Murine Filariasis but Does Not Increase the Recovery Rate for Primary Infection

To establish the role of B cells and antibodies in destroying filariae, mice lacking mature B cells and therefore unable to produce antibodies were used. Litomosoides sigmodontis offers a good opportunity for this study because it is the only filarial species that completes its life cycle in mice. I...

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Autori principali: Martin, Coralie, Saeftel, Michael, Vuong, Phat N., Babayan, Simon, Fischer, Kerstin, Bain, Odile, Hoerauf, Achim
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Fungal and Parasitic Infections
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC100087/
https://ncbi.nlm.nih.gov/pubmed/11598082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.11.7067-7073.2001
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