miR-221 affects multiple cancer pathways by modulating the level of hundreds messenger RNAs

microRNA miR-221 is frequently over-expressed in a variety of human neoplasms. Aim of this study was to identify new miR-221 gene targets to improve our understanding on the molecular tumor-promoting mechanisms affected by miR-221. Gene expression profiling of miR-221-transfected-SNU-398 cells was a...

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Autori principali: Laura eLupini, Cristian eBassi, Manuela eFerracin, Nenad eBartonicek, Lucilla eD'Abundo, Barbara eZagatti, Elisa eCallegari, Gentian eMusa, Farzaneh eMoshiri, Laura eGramantieri, Fernando José Corrales, Anton James Enright, Silvia eSabbioni, Massimo eNegrini
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2013-04-01
Serie:Frontiers in Genetics
Soggetti:
Microarray
microRNA
miR-221
Sylamer
gene targets
Accesso online:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00064/full
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