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Removing batch effects in analysis of expression microarray data: an evaluation of six batch adjustment methods.

The expression microarray is a frequently used approach to study gene expression on a genome-wide scale. However, the data produced by the thousands of microarray studies published annually are confounded by "batch effects," the systematic error introduced when samples are processed in mul...

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Auteurs principaux: Chao Chen, Kay Grennan, Judith Badner, Dandan Zhang, Elliot Gershon, Li Jin, Chunyu Liu
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2011-02-01
Collection:PLoS ONE
Accès en ligne:http://europepmc.org/articles/PMC3046121?pdf=render
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