Diesel Particulate Matter 2.5 Induces Epithelial-to-Mesenchymal Transition and Upregulation of SARS-CoV-2 Receptor during Human Pluripotent Stem Cell-Derived Alveolar Organoid Development

Growing evidence links prenatal exposure to particulate matter (PM2.5) with reduced lung function and incidence of pulmonary diseases in infancy and childhood. However, the underlying biological mechanisms of how prenatal PM2.5 exposure affects the lungs are incompletely understood, which explains t...

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Main Authors: Jung-Hyun Kim, Jeeyoung Kim, Woo Jin Kim, Yung Hyun Choi, Se-Ran Yang, Seok-Ho Hong
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2020-11-01
Series:International Journal of Environmental Research and Public Health
Assuntos:
dPM2.5
EMT
alveolar organoid
human pluripotent stem cells
fibrosis
Acceso en liña:https://www.mdpi.com/1660-4601/17/22/8410
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